Diagnosis and Surgical Management of Renal Tumors Ebook

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Renal cell carcinoma RCC is the most common primary malignancy of the kidney with an estimated 64000 new cases diagnosed each year in the United States Worldwide this figure approaches 270000 annual incident cases At the time of initial presentation 80 of patients with RCC will be diagnosed with a tumor localized the kidney The majority of these lesions will be small ie 4 cm and potentially curable with either partial or radical nephrectomy In recent decades the rate of incidentally detected small renal tumors has risen substantially due the increasing use of cross-sectional imaging performed across the field of medicine This rise in the incident number of localized renal tumors has unfortunately not resulted in a corresponding decrease in cases of metastatic RCC This observation has led to our understanding that a significant proportion of incidentally detected renal tumors are of low malignant potential and may be safely managed with alternatives to surgery such active surveillance and thermo ablation The use of these less invasive management approaches however must be balanced by the reality that upon spreading beyond the confines of the kidney RCC is almost always incurable Thus when selecting a management strategy for a given patient one must employ a risk-adapted approach that includes knowledge of a tumors histology and metastatic potential In each patient the goal of management should be to minimize the risk of progression to metastatic disease while preserving renal function and minimizing morbidity This text provides a contemporary review of the diagnosis and surgical management of RCC It opens with chapters on the pathology radiology and genetics of RCC It then covers the risk stratification of renal tumors utilizing renal mass biopsy as well as non-invasive novel imaging-based scoring systems Next the surgical management of small and locally advanced renal tumors as well as the role of surgery in cases of metastatic RCC is reviewed In addition alternative approaches to surgery including active surveillance and ablative techniques are reviewed Other chapters detail the emerging role of neoadjuvant and adjuvant systemic therapy in patients who are at high risk of progression to metastatic disease Finally the text covers the post-operative surveillance of patients with RCC as well as a summary of contemporary guidelines on the management of this disease Diagnosis and Surgical Management of Renal Cell Carcinoma will serve as a comprehensive resource for physicians and researchers interested in RCC All chapters will be written by experts in the field and will include the most up to date scientific and clinical informationDiagnosis and Surgical Management of Renal Tumors EbookBy Michael A Gorin Publisher Springer Print ISBN 9783319923086 3319923080 eText ISBN 9783319923093 3319923099 Copyright year 2019 Format EPUB Available from 13900 USD SKU 9783319923093

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9783319923086

Renal cell carcinoma RCC is the most common primary malignancy of the kidney with an estimated 64000 new cases diagnosed each year in the United States Worldwide this figure approaches 270000 annual incident cases At the time of initial presentation 80 of patients with RCC will be diagnosed with a tumor localized the kidney The majority of these lesions will be small ie 4 cm and potentially curable with either partial or radical nephrectomy In recent decades the rate of incidentally detected small renal tumors has risen substantially due the increasing use of cross-sectional imaging performed across the field of medicine This rise in the incident number of localized renal tumors has unfortunately not resulted in a corresponding decrease in cases of metastatic RCC This observation has led to our understanding that a significant proportion of incidentally detected renal tumors are of low malignant potential and may be safely managed with alternatives to surgery such active surveillance and thermo ablation The use of these less invasive management approaches however must be balanced by the reality that upon spreading beyond the confines of the kidney RCC is almost always incurable Thus when selecting a management strategy for a given patient one must employ a risk-adapted approach that includes knowledge of a tumors histology and metastatic potential In each patient the goal of management should be to minimize the risk of progression to metastatic disease while preserving renal function and minimizing morbidity This text provides a contemporary review of the diagnosis and surgical management of RCC It opens with chapters on the pathology radiology and genetics of RCC It then covers the risk stratification of renal tumors utilizing renal mass biopsy as well as non-invasive novel imaging-based scoring systems Next the surgical management of small and locally advanced renal tumors as well as the role of surgery in cases of metastatic RCC is reviewed In addition alternative approaches to surgery including active surveillance and ablative techniques are reviewed Other chapters detail the emerging role of neoadjuvant and adjuvant systemic therapy in patients who are at high risk of progression to metastatic disease Finally the text covers the post-operative surveillance of patients with RCC as well as a summary of contemporary guidelines on the management of this disease Diagnosis and Surgical Management of Renal Cell Carcinoma will serve as a comprehensive resource for physicians and researchers interested in RCC All chapters will be written by experts in the field and will include the most up to date scientific and clinical informationDiagnosis and Surgical Management of Renal Tumors EbookBy Michael A Gorin Publisher Springer Print ISBN 9783319923086 3319923080 eText ISBN 9783319923093 3319923099 Copyright year 2019 Format EPUB Available from 13900 USD SKU 9783319923093